Day 1 more IL2 and Stem Cells   October 7th, 2011

From Linda…

Jake had a rough night. I was thankfully he avoided the rigors after Il2 dose #2 and #3. He developed chills about 1.5 hours after each but a quick wrap-up with heated blankets sent him back to slumber land without more drugs.

While he was sleeping, I skipped out about 9am to grab a shower and breakfast at the Lodge. When I got back with the kids, Jake was awake but looking very weary and drawn. The nurses and doctors were concerned that his lungs were suffering from water retention which was causing labored breathing. They put him on oxygen, took some chest x-rays, and began a close watch on his vitals.

After a careful review, the doctors decided no more IL2 for Jake. Another dose would just worsen his symptoms and land him in the ICU. Although the protocol allows for up to 14 doses (no one makes it that far), the average is 4-6. The doctors were keen to reassure Jake that a strong response to the IL2 means happy active warrior cells, but success is NOT dependent on the number of doses. Those evils rigors on the first dose were a strong response.   The good news is Jake can now start his recovery process.

And even more exciting was the event of the day “Stem Cells”. As you know Jake had Total Body Irradiation (TBI) which wiped out his bone marrow. Today, Jake received back the stem cells collected from his own blood several weeks ago using apherisis. These will repopulate his bone marrow and get his body making blood cells again. This usually takes about 10 days to occur.

I’m spending another night on the fold out bed but we are both looking forward to a little more sleep.


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This entry was posted on Friday, October 7th, 2011 at 22:41 and is filed under Health. You can follow any responses to this entry through the RSS 2.0 feed.Both comments and pings are currently closed.

5 Responses

October 7th, 2011 at 23:16
dara Says:

Hoping for much needed rest for all of you tonight…so you can begin your journey on the road to recovery in earnest!

October 7th, 2011 at 23:56
Barbara Leary Says:

Go stem cells! And, again, thanks for the update Linda. I hope you all get plenty of rest while the stem cells get to work! Love, hugs and best wishes for smooth sailing to recovery and NED!

October 8th, 2011 at 02:42
Dad Says:

Thanks, Linda! It might sound tacky, but love and care of the family is very important remedy in every health recovery. I am one of the examples. Crossing fingers. Kiss Jake for us.
Hugs, Ota

October 8th, 2011 at 07:50
LaDonna Says:

the road to recovery…..what a wonderful thing! to know that now he just needs to rest and get better. I had spoken to my doctors here and they have all echoed the same things. A STRONG response to IL2 is a positive thing. Please tell the warrior cells and the stem cells to get cracking! :D

Love and hugs!


October 8th, 2011 at 15:33
Linda Says:

Thanks for the updates Linda. Tell the Big Guy Kelly and I are rooting for him!

Linda #2